F43.23: Adjustment disorder with mixed anxiety and depressed mood

Billable ICD-10-CM code, FY2027

What ICD-10-CM says

Notes at F43.2, Adjustment disorders (they apply to every code under it)

Includes

  • Culture shock
  • Grief reaction
  • Hospitalism in children

Excludes2 (not part of F43.23; both may be coded)

  • separation anxiety disorder of childhood (F93.0)

What F43.23 covers

F43.23 is for an adjustment disorder where the patient's reaction to a stressor shows both anxiety and low mood. The stressor and the timing are part of the clinician's assessment against the DSM-5-TR criteria.

It is common in behavioral health and primary care. The neighbors are F43.21 (with depressed mood only), F43.22 (with anxiety only), F43.24 (with disturbance of conduct), F43.25 (mixed disturbance of emotions and conduct) and F43.20 (unspecified).

Billing and coding notes

The F43.2 subcategory includes grief reaction and culture shock, and has an excludes2 for separation anxiety disorder of childhood (F93.0). Prolonged grief disorder has its own code (F43.81), so use that when the clinician documents it.

Choose the subtype from the documented symptoms. If the note shows anxiety and depressed mood together, F43.23 is more accurate than F43.20 or either single-symptom code.

Related codes under F43.2

Questions about F43.23

Is F43.23 billable?

Yes. F43.23 is a complete code and needs no further characters.

What is the difference between F43.23 and F41.1?

F43.23 is a reaction to an identifiable stressor with both anxiety and low mood. F41.1 is generalized anxiety disorder, which is not tied to a specific stressor.

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ICD-10-CM in CloudMedico

In CloudMedico, a visit's diagnoses come from the current ICD-10-CM list. For US practices, the visit flags a code that isn't billable on its date, and a superbill made from an invoice carries the visit's diagnoses.

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ICD-10-CM FY2027, code descriptions file, CDC National Center for Health Statistics, effective October 1, 2026. ICD-10-CM is in the public domain.

Official text: ICD-10-CM FY2027 tabular list, CDC National Center for Health Statistics, effective October 1, 2026. The summary, notes and answers on this page are CloudMedico's.