E78.2: Mixed hyperlipidemia
Billable ICD-10-CM code, FY2027
What ICD-10-CM says
Includes
- Broad- or floating-betalipoproteinemia
- Combined hyperlipidemia NOS
- Elevated cholesterol with elevated triglycerides NEC
- Fredrickson's hyperlipoproteinemia, type IIb or III
- Hyperbetalipoproteinemia with prebetalipoproteinemia
- Hypercholesteremia with endogenous hyperglyceridemia
- Hyperlipidemia, group C
- Tubo-eruptive xanthoma
- Xanthoma tuberosum
Excludes1 (never coded with E78.2)
- cerebrotendinous cholesterosis [van Bogaert-Scherer- Epstein] (E75.5)
- familial combined hyperlipidemia (E78.49)
Notes at E78, Disorders of lipoprotein metabolism and other lipidemias (they apply to every code under it)
Excludes1 (never coded with E78.2)
- sphingolipidosis (E75.0-E75.3)
What E78.2 covers
E78.2 is for mixed hyperlipidemia: raised cholesterol together with raised triglycerides. It includes combined hyperlipidemia NOS, elevated cholesterol with elevated triglycerides NEC and Fredrickson type IIb or III.
Primary care, cardiology and endocrinology use it. Pure hypercholesterolemia is E78.0-, pure hyperglyceridemia E78.1 and hyperlipidemia with no detail E78.5.
Billing and coding notes
E78.2 has an excludes1 for familial combined hyperlipidemia (E78.49) and cerebrotendinous cholesterosis (E75.5). If the provider documents the familial form, use E78.49 instead.
Use E78.2 when the documentation shows both lipids raised. If the note only says hyperlipidemia, the code is E78.5, unless the provider adds detail.
Related codes under E78
- E78.0 Pure hypercholesterolemia
- E78.1 Pure hyperglyceridemia
- E78.3 Hyperchylomicronemia
- E78.4 Other hyperlipidemia
- E78.5 Hyperlipidemia, unspecified
- E78.6 Lipoprotein deficiency
- E78.7 Disorders of bile acid and cholesterol metabolism
- E78.8 Other disorders of lipoprotein metabolism
- E78.9 Disorder of lipoprotein metabolism, unspecified
Questions about E78.2
What is the difference between E78.2 and E78.5?
E78.2 is mixed hyperlipidemia, with cholesterol and triglycerides both raised. E78.5 is hyperlipidemia with the type not stated.
Is familial combined hyperlipidemia coded E78.2?
No. Familial combined hyperlipidemia is an excludes1 at E78.2 and is coded E78.49.
ICD-10-CM in CloudMedico
In CloudMedico, a visit's diagnoses come from the current ICD-10-CM list. For US practices, the visit flags a code that isn't billable on its date, and a superbill made from an invoice carries the visit's diagnoses.
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